A functional edge Professor Wendy Bickmore, Medical Research Council, Human Genetics Unit has been awarded an Advanced grant of €1.7m from the European Research Council (ERC). These 5 year grants are designed to support, innovative investigator-initiated research projects by leading established investigators in Europe.
The grant entitled “Functional Edge” will investigate how the very edge of the cell nucleus affects the functions of the genome. This leads on from Wendy’s original observation ten years ago, that human chromosomes are not randomly arranged but that certain chromosomes are preferentially located at the edge of the nucleus, whilst others locate far away. Half of the grant will be used to follow up recent findings from Wendy’s lab that positioning a gene against the edge of the nucleus can impede that gene’s expression and will ask how important this spatial information is in development. The rest of the grant will tackle the neglected idea that the edge of the nucleus has a role in protecting parts of our genome from DNA damage. Wendy said:
The research will open up new horizons on our understanding of the multiple levels of control through which genes and genome stability are regulated and the implications of this in both development and disease.
ERC Advanced Investigators Grant
Professor Wendy Bickmore, MRC Human Genetics Unit research page
Elected to EMBO: 22 October 2009
Osteoporosis and coeliac disease: 9 October 2009
Gala awards for innovators:19 August 2009
Major investment genetics and genomics research:
2 June 2009
Genetic Clues Key to Schizophrenia Treatment:
9 March 2009
The Future Of Cancer Treatment: Can We Afford It?: March 2009
IGMM Workshop: February 2009
Scientist's quest to ease Bone Patients: 16 February 2009
Elected 2010 Balfour Lecturer: 5 February 2009
Untangling the String: 5 February 2009
Study sheds light on cause of Bowel Disease:
10 December 2008
Study sheds light on cause of bowel disease: 10 December 2008
IGMM Communications Group: December 2008
IGMM Retreat: 15 October 2008
PhD Student Award: 1 October 2008
Royal Society Awards: August 2008
Breast Cancer World Class Research Unit: 4 June 2008Genetics of Inflammatory Bowel Disease: 14 May 2008
Racial Differences in Response to Bowel Cancer Genetic Risk Factor: 1 April 2008
Osteoporosis Research Investigating Effects of Cannabis Drug on Thinning Bones: 26 March 2008
New Support for DISC1: 13 March 2008
Award Winning Images of Science: 12 Mar 2008
Gene Could Spell New Chapter in Fight Against Gout: 10 Mar 08
New Fellows: The Royal Society of Edinburgh
7 Mar 08
MRC Centre in Cognitive Ageing and Cognitive Epidemiology: 5 Mar 2008
Dr Matt Cockerill: 7 Feb 08
Professor Sir Ian Wilmut: 24 Jan 08
The Centre for Molecular Medicine is delighted to announce that Professor Jack Satsangi has been elected a Fellow of the Royal Society of Edinburgh.
Professor Jack Satsangi's election recognises his outstanding work in inflammatory bowel disease, in particular his breakthroughs in identifying genetic risk factors for Crohn’s disease.
The Centre for Molecular Medicine
Professor Jack Satsangi, The Centre for Molecular Medicine research page
The Royal Society of Edinburgh:
Fellowship/Election of Fellows 2010