the lab

 

  1. Ratelade, J.; Arrondel, C.; Hamard, G.; Garbay, S.; Harvey, S.; Biebuyck, N.; Schulz, H.; Hastie, N.; Pontoglio, M.; Gubler, M.C.; Antignac, C. and Heidet, L. A MURINE MODEL OF DENYS-DRASH SYNDROME REVEALS NOVEL TRANSCRIPTIONAL TARGETS OF WT1 IN PODOCYTES.
    Hum.Mol.Genet.     19(1):1-15, 2010
    PubMed Abstract
  2. Repapi, E.; Sayers, I.; Wain, L.V.; Burton, P.R.; Johnson, T.; Obeidat, M.; Zhao, J.H.; Ramasamy, A.; Zhai, G.; Vitart, V.; Huffman, J.E.; Igl, W.; Albrecht, E.; Deloukas, P.; Henderson, J.; Granell, R.; McArdle, W.L.; Rudnicka, A.R.; Barroso, I.; Loos, R.J.; Wareham, N.J.; Mustelin, L.; Rantanen, T.; Surakka, I.; Imboden, M.; Wichmann, H.E.; Grkovic, I.; Jankovic, S.; Zgaga, L.; Hartikainen, A.L.; Peltonen, L.; Gyllensten, U.; Johansson, A.; Zaboli, G.; Campbell, H.; Wild, S.H.; Wilson, J.F.; Glaser, S.; Homuth, G.; Volzke, H.; Mangino, M.; Soranzo, N.; Spector, T.D.; Polasek, O.; Rudan, I.; Wright, A.F.; Heliovaara, M.; Ripatti, S.; Pouta, A.; Naluai, A.T.; Olin, A.C.; Toren, K.; Cooper, M.N.; James, A.L.; Palmer, L.J.; Hingorani, A.D.; Wannamethee, S.G.; Whincup, P.H.; Smith, G.D.; Ebrahim, S.; McKeever, T.M.; Pavord, I.D.; MacLeod, A.K.; Morris, A.D.; Porteous, D.J.; Cooper, C.; Dennison, E.; Shaheen, S.; Karrasch, S.; Schnabel, E.; Schulz, H.; Grallert, H.; Bouatia-Naji, N.; Delplanque, J.; Froguel, P.; Blakey, J.D.; Britton, J.R.; Morris, R.W.; Holloway, J.W.; Lawlor, D.A.; Hui, J.; Nyberg, F.; Jarvelin, M.R.; Jackson, C.; Kahonen, M.; Kaprio, J.; Probst-Hensch, N.M.; Koch, B.; Hayward, C.; Evans, D.M.; Elliott, P.; Strachan, D.P.; Hall, I.P. and Tobin, M.D. Genome-wide association study identifies five loci associated with lung function.
    Nat.Genet.     42(1):36-44, 2010
    PubMed Abstract
  3. Richardson, L.; Venkataraman, S.; Stevenson, P.; Yang, Y.; Burton, N.; Rao, J.; Fisher, M.; Baldock, R.A.; Davidson, D.R. and Christiansen, J.H. EMAGE mouse embryo spatial gene expression database: 2010 update
    Nucleic Acids Res 38(Database issue):
    D703-D709, 2010
    PubMed Abstract
  4. Schmidt, C.Q.; Herbert, A.P.; Mertens, H.D.; Guariento, M.; Soares, D.C.; Uhrin, D.; Rowe, A.J.; Svergun, D.I. and Barlow, P.N. The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module. J Mol.Biol 395(1):105-122, 2010
    PubMed Abstract
  5. Shu, X.; Zeng, Z.; Gautier, P.; Lennon, A.; Gakovic, M.; Patton, E.E. and Wright, A.F. Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processes. Hum.Mol.Genet. 19(4):657-670, 2010
    PubMed Abstract
  6. Thoms, H.C.; Loveridge, C.J.; Simpson, J.; Clipson, A.; Reinhardt, K.; Dunlop, M.G. and Stark, L.A. Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination
    Cancer Res 70(1):139-149, 2010
    PubMed Abstract
  7. Tyrrell, C.; De Cecco, M.; Reynolds, N.L.; Kilanowski, F.; Campopiano, D.; Barran, P.; MacMillan, D. and Dorin, J.R. Isoleucine/leucine(2) is essential for chemoattractant activity of beta-defensin Defb14 through chemokine receptor 6
    Mol. Immunol. 47(6):1378-1382, 2010
    PubMed Abstract
  8. Vitart, V.; Bencic, G.; Hayward, C.; Herman, J.S.; Huffman, J.E.; Campbell, S.; Bucan, K.; Zgaga, L.; Kolcic, I.; Polasek, O.; Campbell, H.; Wright, A.F.; Vatavuk, Z. and Rudan, I. Heritabilities of ocular biometrical traits in 2 Croatian isolates with extended pedigrees. Invest Ophthalmol Vis Sci.51(2):737-43, 2010
    PubMed Abstract



Related Links
IGMM news and events

Publications 2010

  1. Baglietto, L.; Lindor, N.M.; Dowty, J.G.; White, D.M.; Wagner, A.; Gomez Garcia, E.B.; Vriends, A.H.; Cartwright, N.R.; Barnetson, R.A.; Farrington, S.M.; Tenesa, A.; Hampel, H.; Buchanan, D.; Arnold, S.; Young, J.; Walsh, M.D.; Jass, J.; Macrae, F.; Antill, Y.; Winship, I.M.; Giles, G.G.; Goldblatt, J.; Parry, S.; Suthers, G.; Leggett, B.; Butz, M.; Aronson, M.; Poynter, J.N.; Baron, J.A.; Le Marchand, L.; Haile, R.; Gallinger, S.; Hopper, J.L.; Potter, J.; de la, C.A.; Vasen, H.F.; Dunlop, M.G.; Thibodeau, S.N. and Jenkins, M.A. Risks of Lynch syndrome cancers for MSH6 mutation carriers
    J Natl.Cancer Inst. 102(3):193-201, 2010

  2. Bovellan, M.; Fritzsche, M.; Stevens, C. and Charras, G. Death-associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death
    FEBS Journall  277(1):58-65, 2010
    PubMed Abstract
  3. Carrasquillo, M.M.; Belbin, O.; Zou, F.; Allen, M.; Ertekin-Taner, N.; Ansari, M.; Wilcox, S.L.; Kashino, M.R.; Ma, L.; Younkin, L.H.; Younkin, S.G.; Younkin, C.S.; Dincman, T.A.; Howard, M.E.; Howell, C.C.; Stanton, C.M.; Watson, C.M.; Crump, M.; Vitart, V.; Hayward, C.; Hastie, N.D.; Rudan, I.; Campbell, H.; Polasek, O.; Brown, K.; Passmore, P.; Craig, D.; McGuinness, B.; Todd, S.; Kehoe, P.G.; Mann, D.M.; Smith, A.D.; Beaumont, H.; Warden, D.; Holmes, C.; Heun, R.; Kolsch, H.; Kalsheker, N.; Pankratz, V.S.; Dickson, D.W.; Graff-Radford, N.R.; Petersen, R.C.; Wright, A.F.; Younkin, S.G. and Morgan, K. Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease
    PLoS One. 5(1):e8764, 2010
    PubMed Abstract
  4. Dudnakova, T.; Spraggon, L.; Slight, J. and Hastie, N. Actin: a novel interaction partner of WT1 influencing its cell dynamic properties. Oncogene 29(7):1085-92, 2010
    PubMed Abstract
  5. Dupuis, J.; Langenberg, C.; ....Navarro, P.; .........Hayward, C.; ......... Vitart, V.; ...... Wright, A.F.:...........and Barroso, I. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
    Nat.Genet.     42(2):105-116, 2010
    PubMed Absract
  6. Essafi, A. and Hastie, N.D. WT1 the Oncogene: A Tale of Death and HtrA.
    Mol.Cell     37(2):153-155, 2010
    PubMed Abstract
  7. Faull, P. A.; Florance, H. V.; Schmidt, C. Q.; Tomczyk, N.; Barlow, P. N.; Hupp, T. R.; Nikolova, P. V., and Barran, P. E. Utilising ion mobility-mass spectrometry to interrogate macromolecules: Factor H complement control protein modules 10–15 and 19–20 and the DNA-binding core domain of tumour suppressor p53. International Journal of Mass Spectrometry 2010
  8. Harewood, L.; Keeling, J.W.; Fantes, J.A.; Opitz, J.M. and Fitzpatrick, D.R. 'Crommelin-type' symmetrical tetramelic reduction deformity: a new case and breakpoint mapping of a reported case with de-novo t(2;12)(p25.1;q23.3).
    Clin.Dysmorphol.     19(1):5-13, 2010
    PubMed Abstract
  9. Hupp, T.R. Death-associated protein kinase (DAPK) and signal transduction
    FEBS Journal 277(1):47, 2010
    PubMed Abstract
  10. Igl, W.; Johansson, A.; Wilson, J.F.; Wild, S.H.; Polasek, O.; Hayward, C.; Vitart, V.; Hastie, N.; Rudan, P.; Gnewuch, C.; Schmitz, G.; Meitinger, T.; Pramstaller, P.P.; Hicks, A.A.; Oostra, B.A.; van Duijn, C.M.; Rudan, I.; Wright, A.; Campbell, H. and Gyllensten, U. Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels. PLoS Genet. 6(1):e1000798, 2010 PubMed Abstract
  11. Lin, Y.; Hupp, T.R. and Stevens, C. Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death
    FEBS Journal 277(1):48-57, 2010
    PubMed Abstract
  12. Luciano, M.; Houlihan, L.M.; Harris, S.E.; Gow, A.J.; Hayward, C.; Starr, J.M. and Deary, I.J. Association of Existing and New Candidate Genes for Anxiety, Depression and Personality Traits in Older People
    Behav Genet e-pub Jan 6    , 2010
    PubMed Abstract
  13. Martinez-Estrada, O.M.; Lettice, L.A.; Essafi, A.; Guadix, J.A.; Slight, J.; Velecela, V.; Hall, E.; Reichmann, J.; Devenney, P.S.; Hohenstein, P.; Hosen, N.; Hill, R.E.; Munoz-Chapuli, R. and Hastie, N.D. Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
    Nat.Genet. 42(1):89-93, 2010
    PubMed Abstract
  14. Navarro, P.; Vitart, V.; Hayward, C.; Tenesa, A.; Zgaga, L.; Juricic, D.; Polasek, O.; Hastie, N.D.; Rudan, I.; Campbell, H.; Wright, A.F.; Haley, C.S. and Knott, S.A. Genetic comparison of a Croatian isolate and CEPH European founders. Genet.Epidemiol 34(2):140-5, 2010
    PubMed Abstract
  15. Patton, E.E. and Nairn, R.S. Xmrk in medaka: a new genetic melanoma model.
    J Invest Dermatol.     130(1):14-17, 2010
    PubMed Abstract