the lab

 

  1. Luciano, M.; Houlihan, L.M.; Harris, S.E.; Gow, A.J.; Hayward, C.; Starr, J.M. and Deary, I.J. Association of Existing and New Candidate Genes for Anxiety, Depression and Personality Traits in Older People
    Behav Genet e-pub Jan 6    , 2010
    PubMed Abstract
  2. Lunse, C.E.; Michlewski, G.; Hopp, C.S.; Rentmeister, A.; Caceres, J.F.; Famulok, M. and Mayer, G. An Aptamer Targeting the Apical-Loop Domain Modulates. Angewandte Chemie International Edition 49(1):1-5, 2010
  3. Martinez-Estrada, O.M.; Lettice, L.A.; Essafi, A.; Guadix, J.A.; Slight, J.; Velecela, V.; Hall, E.; Reichmann, J.; Devenney, P.S.; Hohenstein, P.; Hosen, N.; Hill, R.E.; Munoz-Chapuli, R. and Hastie, N.D. Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
    Nat.Genet. 42(1):89-93, 2010
    PubMed Abstract
  4. McCullough, B.J.; Kalapothakis, J.M.; Chin, W.; Taylor, K.; Clarke, D.J.; Eastwood, H.; Campopiano, D.; MacMillan, D.; Dorin, J. and Barran, P.E. Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements. Phys.Chem.Chem.Phys. 12(14):3589-3596, 2010
    PubMed Abstract
  5. Mitchell, K.J. and Porteous, D.J. Rethinking the genetic architecture of schizophrenia. Psychol.Med:1-14, 2010
    PubMed Abstract
  6. Mort, R.L.; Hay, L. and Jackson, I.J. Ex-vivo live imaging of melanoblast migration in embryonic mouse skin. Pigment Cell Melanoma Res 23(2):229-301, 2010
    PubMed Abstract
  7. Morton, J.P.; Timpson, P.; Karim, S.A.; Ridgway, R.A.; Athineos, D.; Doyle, B.; Jamieson, N.B.; Oien, K.A.; Lowy, A.M.; Brunton, V.G.; Frame, M.C.; Evans, T.R. and Sansom, O.J. Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer. Proc.Natl.Acad.Sci.U.S.A 107(1):246-251, 2010
    PubMed Abstract
  8. Navarro, P.; Vitart, V.; Hayward, C.; Tenesa, A.; Zgaga, L.; Juricic, D.; Polasek, O.; Hastie, N.D.; Rudan, I.; Campbell, H.; Wright, A.F.; Haley, C.S. and Knott, S.A. Genetic comparison of a Croatian isolate and CEPH European founders. Genet.Epidemiol 34(2):140-5, 2010
    PubMed Abstract
  9. Nestor, C.; Ruzov, A.; Meehan, R.R. and Dunican, D.S. Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethlcytosine in DNA. BioTechniques 48(4):317-319, 2010
  10. Ollinger, R.; Reichmann, J. and Adams, I.R. Meiosis and retrotransposon silencing during germ cell development in mice.
    Differentiation     79(3):147-158, 2010
    PubMed Abstract
  11. Paige, A.J.; Zucknick, M.; Janczar, S.; Paul, J.; Mein, C.A.; Taylor, K.J.; Stewart, M.; Gourley, C.; Richardson, S.; Perren, T.; Ganesan, T.S.; Smyth, J.F.; Brown, R. and Gabra, H. WWOX tumour suppressor gene polymorphisms and ovarian cancer pathology and prognosis.
    Eur.J Cancer      46(4):818-825, 2010
    PubMed Abstract
  12. Pattaro, C.; De Grandi, A.; Vitart, V.; Hayward, C.; Franke, A.; Aulchenko, Y.S.; Johansson, A.; Wild, S.H.; Melville, S.A.; Isaacs, A.; Polasek, O.; Ellinghaus, D.; Kolcic, I.; Nothlings, U.; Zgaga, L.; Zemunik, T.; Gnewuch, C.; Schreiber, S.; Campbell, S.; Hastie, N.; Boban, M.; Meitinger, T.; Oostra, B.A.; Riegler, P.; Minelli, C.; Wright, A.F.; Campbell, H.; van Duijn, C.M.; Gyllensten, U.; Wilson, J.F.; Krawczak, M.; Rudan, I. and Pramstaller, P.P. A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. BMC Med Genet. 11:41, 2010
    PubMed Abstract
  13. Patton, E.E.; Mitchell, D.L. and Nairn, R.S. Genetic and Environmental Melanoma Models in Fish.
    Pigment Cell Melanoma Res     23:314-337, 2010
    PubMed Abstract
  14. Patton, E.E. and Nairn, R.S. Xmrk in medaka: a new genetic melanoma model.
    J Invest Dermatol.     130(1):14-17, 2010
    PubMed Abstract
  15. Phillips, A.M.; Nimmo, E.R.; Van Limbergen, J.; Drummond, H.E.; Smith, L. and Satsangi, J. Detailed haplotype-tagging study of germline variation of MUC19 in inflammatory bowel disease.
    Inflamm.Bowel.Dis 16(4):557-558, 2010 PubMed Abstract
  16. Polasek, O.; Hayward, C.; Bellenguez, C.; Vitart, V.; Kolcic, I.; McQuillan, R.; Saftic, V.; Gyllensten, U.; Wilson, J.F.; Rudan, I.; Wright, A.F.; Campbell, H. and Leutenegger, A.L. Comparative assessment of methods for estimating individual genome-wide homozygosity-by-descent from human genomic data. BMC Genomics 11:139, 2010
    Pubmed Abstract
  17. Ralston, S.H. and Uitterlinden, A.G. Genetics of Osteoporosis. Endocr.Rev. e-pub April 29, 2010 PubMed Abstract
  18. Ralston, S.H. Genetics of osteoporosis. Ann.N.Y.Acad.Sci. 1192(1):181-189, 2010 PubMed Abstract
  19. Ralston, S. H. Osteoporosis as an Heriditary Disease. Clinical Reviews in Bone and Mineral Metabolism. e-pub 1-9, 2010
  20. Ratelade, J.; Arrondel, C.; Hamard, G.; Garbay, S.; Harvey, S.; Biebuyck, N.; Schulz, H.; Hastie, N.; Pontoglio, M.; Gubler, M.C.; Antignac, C. and Heidet, L. A MURINE MODEL OF DENYS-DRASH SYNDROME REVEALS NOVEL TRANSCRIPTIONAL TARGETS OF WT1 IN PODOCYTES.
    Hum.Mol.Genet.     19(1):1-15, 2010
    PubMed Abstract
  21. Repapi, E.; Sayers, I.; Wain, L.V.; Burton, P.R.; Johnson, T.; Obeidat, M.; Zhao, J.H.; Ramasamy, A.; Zhai, G.; Vitart, V.; Huffman, J.E.; Igl, W.; Albrecht, E.; Deloukas, P.; Henderson, J.; Granell, R.; McArdle, W.L.; Rudnicka, A.R.; Barroso, I.; Loos, R.J.; Wareham, N.J.; Mustelin, L.; Rantanen, T.; Surakka, I.; Imboden, M.; Wichmann, H.E.; Grkovic, I.; Jankovic, S.; Zgaga, L.; Hartikainen, A.L.; Peltonen, L.; Gyllensten, U.; Johansson, A.; Zaboli, G.; Campbell, H.; Wild, S.H.; Wilson, J.F.; Glaser, S.; Homuth, G.; Volzke, H.; Mangino, M.; Soranzo, N.; Spector, T.D.; Polasek, O.; Rudan, I.; Wright, A.F.; Heliovaara, M.; Ripatti, S.; Pouta, A.; Naluai, A.T.; Olin, A.C.; Toren, K.; Cooper, M.N.; James, A.L.; Palmer, L.J.; Hingorani, A.D.; Wannamethee, S.G.; Whincup, P.H.; Smith, G.D.; Ebrahim, S.; McKeever, T.M.; Pavord, I.D.; MacLeod, A.K.; Morris, A.D.; Porteous, D.J.; Cooper, C.; Dennison, E.; Shaheen, S.; Karrasch, S.; Schnabel, E.; Schulz, H.; Grallert, H.; Bouatia-Naji, N.; Delplanque, J.; Froguel, P.; Blakey, J.D.; Britton, J.R.; Morris, R.W.; Holloway, J.W.; Lawlor, D.A.; Hui, J.; Nyberg, F.; Jarvelin, M.R.; Jackson, C.; Kahonen, M.; Kaprio, J.; Probst-Hensch, N.M.; Koch, B.; Hayward, C.; Evans, D.M.; Elliott, P.; Strachan, D.P.; Hall, I.P. and Tobin, M.D. Genome-wide association study identifies five loci associated with lung function.
    Nat.Genet.     42(1):36-44, 2010
    PubMed Abstract
  22. Richardson, L.; Venkataraman, S.; Stevenson, P.; Yang, Y.; Burton, N.; Rao, J.; Fisher, M.; Baldock, R.A.; Davidson, D.R. and Christiansen, J.H. EMAGE mouse embryo spatial gene expression database: 2010 update
    Nucleic Acids Res 38(Database issue):
    D703-D709, 2010
    PubMed Abstract
  23. Riches, P.L. and Ralston, S.H. Recent insights into the biology of bone turnover. Journal of the Royal College of Pysicians Edinburgh 40(1):66-69, 2010
  24. Sabine, V.S.; Sims, A.H.; Macaskill, E.J.; Renshaw, L.; Thomas, J.S.; Dixon, J.M. and Bartlett, J.M. Gene expression profiling of response to mTOR inhibitor everolimus in pre-operatively treated post-menopausal women with oestrogen receptor-positive breast cancer Breast Cancer Res Treat. May 18, 2010
    PubMed Abstract
  25. Schmidt, C.Q.; Herbert, A.P.; Mertens, H.D.; Guariento, M.; Soares, D.C.; Uhrin, D.; Rowe, A.J.; Svergun, D.I. and Barlow, P.N. The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module. J Mol.Biol 395(1):105-122, 2010
    PubMed Abstract
  26. Semple, F.; Webb, S.; Li, H.N.; Patel, H.B.; Perretti, M.; Jackson, I.J.; Gray, M.; Davidson, D.J. and Dorin, J.R. Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo. Eur.J Immunol. 40(4):1073-1078, 2010 PubMed Abstract
  27. Serrels, B.; Sandilands, E.; Serrels, A.; Baillie, G.; Houslay, M.D.; Brunton, V.G.; Canel, M.; Machesky, L.M.; Anderson, K.I. and Frame, M.C. A Complex between FAK, RACK1, and PDE4D5 Controls Spreading Initiation and Cancer Cell Polarity.
    Curr.Biol     e-pub May 19, 2010
    PubMed Abstract
  28. Shu, X.; Zeng, Z.; Gautier, P.; Lennon, A.; Gakovic, M.; Patton, E.E. and Wright, A.F. Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processes. Hum.Mol.Genet. 19(4):657-670, 2010
    PubMed Abstract
  29. Sudlow, C.; Macleod, M.; Al Shahi, S.R. and Stone, J. Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"
    Science     28(5980):825, 2010
    PubMed Abstract
  30. Theodoratou, E.; Din, F.V.; Farrington, S.M.; Cetnarskyj, R.; Barnetson, R.A.; Porteous, M.E.; Dunlop, M.G.; Campbell, H. and Tenesa, A. Association between common mtDNA variants and all-cause or colorectal cancer mortality. Carcinogenesis 31(2):296-301, 2010
    PubMed Abstract
  31. Thoms, H.C.; Loveridge, C.J.; Simpson, J.; Clipson, A.; Reinhardt, K.; Dunlop, M.G. and Stark, L.A. Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination
    Cancer Res 70(1):139-149, 2010
    PubMed Abstract
  32. Tyrrell, C.; De Cecco, M.; Reynolds, N.L.; Kilanowski, F.; Campopiano, D.; Barran, P.; MacMillan, D. and Dorin, J.R. Isoleucine/leucine(2) is essential for chemoattractant activity of beta-defensin Defb14 through chemokine receptor 6
    Mol. Immunol. 47(6):1378-1382, 2010
    PubMed Abstract
  33. van Agtmael, T.; Bailey, M.A.; Schlotzer-Schrehardt, U.; Craigie, E.; Jackson, I.J.; Brownstein, D.G.; Megson, I.L. and Mullins, J.J. Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume.
    Hum.Mol.Genet. 19(6):1119-1128, 2010 PubMed Abstract
  34. van Agtmael, T.; Bailey, M.A.; Schlotzer-Schrehardt, U.; Craigie, E.; Jackson, I.J.; Brownstein, D.G.; Megson, I.L. and Mullins, J.J. Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume.
    Hum.Mol.Genet. 19(6):1119-1128, 2010 PubMed Abstract
  35. Vitart, V.; Bencic, G.; Hayward, C.; Herman, J.S.; Huffman, J.E.; Campbell, S.; Bucan, K.; Zgaga, L.; Kolcic, I.; Polasek, O.; Campbell, H.; Wright, A.F.; Vatavuk, Z. and Rudan, I. Heritabilities of ocular biometrical traits in 2 Croatian isolates with extended pedigrees. Invest Ophthalmol Vis Sci.51(2):737-43, 2010
    PubMed Abstract
  36. Walter, T.; Shattuck, D.; Baldock, R.; Bastin, M.; Carpenter, A.E.; Duce, S.; Ellenberg, J.; Fraser, A.; Hamilton, N.; Pieper, S.; Ragan, M.A.; Schneider, J.; Tomancak, P. and Heriche, J. Visualization of image data from cells to organisms. Nature Methods Supplement 7(3):S26-S41, 2010
  37. Welman, A.; Serrels, A.; Brunton, V.G.; Ditzel, M. and Frame, M.C. Two-color photoactivatable probe for selective tracking of proteins and cells. J Biol Chem. 285(15):11607-11616, 2010 PubMed Abstract
  38. Worrall, E.G.; Worrall, L.; Blackburn, E.; Walkinshaw, M. and Hupp, T.R. The effects of phosphomimetic lid mutation on the thermostability of the N-terminal domain of MDM2. J Mol.Biol 398(3):414-428, 2010
    PubMed Abstract
  39. Wright, A.F.; Chakarova, C.F.; Abd El-Aziz, M.M. and Bhattacharya, S.S. Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait.
    Nat.Rev.Genet.     11(4):273-284, 2010
    PubMed Abstract
  40. Yu-Wai-Man, P.; Griffiths, P.G.; Gorman, G.S.; Lourenco, C.M.; Wright, A.F.; Auer-Grumbach, M.; Toscano, A.; Musumeci, O.; Valentino, M.L.; Caporali, L.; Lamperti, C.; Tallaksen, C.M.; Duffey, P.; Miller, J.; Whittaker, R.G.; Baker, M.R.; Jackson, M.J.; Clarke, M.P.; Dhillon, B.; Czermin, B.; Stewart, J.D.; Hudson, G.; Reynier, P.; Bonneau, D.; Marques, W., Jr.; Lenaers, G.; McFarland, R.; Taylor, R.W.; Turnbull, D.M.; Votruba, M.; Zeviani, M.; Carelli, V.; Bindoff, L.A.; Horvath, R.; Amati-Bonneau, P. and Chinnery, P.F. Multi-system neurological disease is common in patients with OPA1 mutations. Brain 133(Pt 3):771-786, 2010 PubMed Abstract



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Publications 2010

  1. Aitken, S.J.; Thomas, J.S.; Langdon, S.P.; Harrison, D.J. and Faratian, D. Quantitative analysis of changes in ER, PR and HER2 expression in primary breast cancer and paired nodal metastases.
    Ann.Oncol.    21(6):1254-61, 2010
    PubMed Abstract
  2. Albagha, O.M.; Visconti, M.R.; Alonso, N.; Langston, A.L.; Cundy, T.; Dargie, R.; Dunlop, M.G.; Fraser, W.D.; Hooper, M.J.; Isaia, G.; Nicholson, G.C.; Del Pino, M.J.; Gonzalez-Sarmiento, R.; di Stefano, M.; Tenesa, A.; Walsh, J.P. and Ralston, S.H. Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone.
    Nat.Genet.     e-pub May 2, 2010
    PubMed Abstract
  3. Baglietto, L.; Lindor, N.M.; Dowty, J.G.; White, D.M.; Wagner, A.; Gomez Garcia, E.B.; Vriends, A.H.; Cartwright, N.R.; Barnetson, R.A.; Farrington, S.M.; Tenesa, A.; Hampel, H.; Buchanan, D.; Arnold, S.; Young, J.; Walsh, M.D.; Jass, J.; Macrae, F.; Antill, Y.; Winship, I.M.; Giles, G.G.; Goldblatt, J.; Parry, S.; Suthers, G.; Leggett, B.; Butz, M.; Aronson, M.; Poynter, J.N.; Baron, J.A.; Le Marchand, L.; Haile, R.; Gallinger, S.; Hopper, J.L.; Potter, J.; de la, C.A.; Vasen, H.F.; Dunlop, M.G.; Thibodeau, S.N. and Jenkins, M.A. Risks of Lynch syndrome cancers for MSH6 mutation carriers
    J Natl.Cancer Inst. 102(3):193-201, 2010
    PubMed Abstract
  4. Bovellan, M.; Fritzsche, M.; Stevens, C. and Charras, G. Death-associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death
    FEBS Journall  277(1):58-65, 2010
    PubMed Abstract
  5. Carrasquillo, M.M.; Belbin, O.; Zou, F.; Allen, M.; Ertekin-Taner, N.; Ansari, M.; Wilcox, S.L.; Kashino, M.R.; Ma, L.; Younkin, L.H.; Younkin, S.G.; Younkin, C.S.; Dincman, T.A.; Howard, M.E.; Howell, C.C.; Stanton, C.M.; Watson, C.M.; Crump, M.; Vitart, V.; Hayward, C.; Hastie, N.D.; Rudan, I.; Campbell, H.; Polasek, O.; Brown, K.; Passmore, P.; Craig, D.; McGuinness, B.; Todd, S.; Kehoe, P.G.; Mann, D.M.; Smith, A.D.; Beaumont, H.; Warden, D.; Holmes, C.; Heun, R.; Kolsch, H.; Kalsheker, N.; Pankratz, V.S.; Dickson, D.W.; Graff-Radford, N.R.; Petersen, R.C.; Wright, A.F.; Younkin, S.G. and Morgan, K. Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease
    PLoS One. 5(1):e8764, 2010
    PubMed Abstract

  6. Christoforou, A.; McGhee, K.A.; Morris, S.W.; Thomson, P.A.; Anderson, S.; McLean, A.; Torrance, H.S.; Le Hellard, S.; Pickard, B.S.; Stclair, D.; Muir, W.J.; Blackwood, D.H.; Porteous, D.J. and Evans, K.L. Convergence of linkage, association and GWAS findings for a candidate region for bipolar disorder and schizophrenia on chromosome 4p. Mol.Psychiatry e-pub march 30, 2010
    PubMed Abstract

  7. De Cecco, M.; Seo, E.S.; Clarke, D.J.; McCullough, B.J.; Taylor, K.; MacMillan, D.; Dorin, J.R.; Campopiano, D.J. and Barran, P.E. Conformational preferences of linear beta-defensins are revealed by ion mobility-mass spectrometry.
    J Phys.Chem.B 114(6):2312-2318, 2010
    PubMed Abstract
  8. Dinour, D.; Gray, N.K.; Campbell, S.; Shu, X.; Sawyer, L.; Richardson, W.; Rechavi, G.; Amariglio, N.; Ganon, L.; Sela, B.A.; Bahat, H.; Goldman, M.; Weissgarten, J.; Millar, M.R.; Wright, A.F. and Holtzman, E.J. Homozygous SLC2A9 mutations cause severe renal hypouricemia.
    J Am.Soc.Nephrol.     21(1):64-72, 2010
    PubMed Abstract
  9. Dudnakova, T.; Spraggon, L.; Slight, J. and Hastie, N. Actin: a novel interaction partner of WT1 influencing its cell dynamic properties. Oncogene 29(7):1085-92, 2010
    PubMed Abstract
  10. Dupuis, J.; Langenberg, C.; ....Navarro, P.; .........Hayward, C.; ......... Vitart, V.; ...... Wright, A.F.:...........and Barroso, I. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
    Nat.Genet.     42(2):105-116, 2010
    PubMed Absract
  11. Eskeland, R.; Leeb, M.; Grimes, G.R.; Kress, C.; Boyle, S.; Sproul, D.; Gilbert, N.; Fan, Y.; Skoultchi, A.I.; Wutz, A. and Bickmore, W.A. Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.
    Mol.Cell 38(3):452-464, 2010
    PubMed Abstract
  12. Essafi, A. and Hastie, N.D. WT1 the Oncogene: A Tale of Death and HtrA.
    Mol.Cell     37(2):153-155, 2010
    PubMed Abstract
  13. Faull, P. A.; Florance, H. V.; Schmidt, C. Q.; Tomczyk, N.; Barlow, P. N.; Hupp, T. R.; Nikolova, P. V., and Barran, P. E. Utilising ion mobility-mass spectrometry to interrogate macromolecules: Factor H complement control protein modules 10–15 and 19–20 and the DNA-binding core domain of tumour suppressor p53. International Journal of Mass Spectrometry 2010
  14. Fong, P.C.; Yap, T.A.; Boss, D.S.; Carden, C.P.; Mergui-Roelvink, M.; Gourley, C.; De Greve, J.; Lubinski, J.; Shanley, S.; Messiou, C.; A'Hern, R.; Tutt, A.; Ashworth, A.; Stone, J.; Carmichael, J.; Schellens, J.H.; de Bono, J.S. and Kaye, S.B. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval.
    J Clin Oncol     28(15):2512-2519, 2010
    PubMed Abstract
  15. Gourley, C.; Michie, C.O.; Roxburgh, P.; Yap, T.A.; Harden, S.; Paul, J.; Ragupathy, K.; Todd, R.; Petty, R.; Reed, N.; Hayward, R.L.; Mitchell, P.; Rye, T.; Schellens, J.H.; Lubinski, J.; Carmichael, J.; Kaye, S.B.; Mackean, M. and Ferguson, M. Increased incidence of visceral metastases in scottish patients with BRCA1/2-defective ovarian cancer: an extension of the ovarian BRCAness phenotype.
    J Clin Oncol     28(15):2505-2511, 2010
    PubMed Abstact
  16. Harewood, L.; Keeling, J.W.; Fantes, J.A.; Opitz, J.M. and Fitzpatrick, D.R. 'Crommelin-type' symmetrical tetramelic reduction deformity: a new case and breakpoint mapping of a reported case with de-novo t(2;12)(p25.1;q23.3).
    Clin.Dysmorphol.     19(1):5-13, 2010
    PubMed Abstract
  17. Harewood, L.; Schutz, F.; Boyle, S.; Perry, P.; Delorenzi, M.; Bickmore, W.A. and Reymond, A. The effect of translocation-induced nuclear reorganization on gene expression.
    Genome Res    , 20:554-564, 2010
    PubMed Abstract
  18. Holder, E.; Stevenson, B.; Farley, R.; Hilliard, T.; Wodehouse, T.; Somerton, L.; Larsen, M.; O'Donoghue, J.; Coles, R.L.; Scheule, R.K.; Cheng, S.H.; Gill, D.R.; Hyde, S.C.; Griesenbach, U.; Alton, E.W.; Porteous, D.J. and Boyd, A.C. Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity.
    J Gene Med 12(1):55-63, 2010
    PubMed Abstract
  19. Houlihan, L.M.; Davies, G.; Tenesa, A.; Harris, S.E.; Luciano, M.; Gow, A.J.; McGhee, K.A.; Liewald, D.C.; Porteous, D.J.; Starr, J.M.; Lowe, G.D.; Visscher, P.M. and Deary, I.J. Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time.
    Am.J Hum.Genet. 86(4):626-631, 2010 PubMed Abstract
  20. Houlihan, L.M.; Wyatt, N.D.; Harris, S.E.; Hayward, C.; Gow, A.J.; Marioni, R.E.; Strachan, M.W.; Price, J.F.; Starr, J.M.; Wright, A.F. and Deary, I.J. Variation in the uric acid transporter gene (SLC2A9) and memory performance.
    Hum.Mol.Genet.     19(11):2321-2330, 2010 PubMed Abstract
  21. Hupp, T.R. Death-associated protein kinase (DAPK) and signal transduction
    FEBS Journal 277(1):47, 2010
    PubMed Abstract
  22. Idris, A.I.; Landao-Bassonga, E. and Ralston, S.H. The TRPV1 ion channel antagonist capsazepine inhibits osteoclast and osteoblast differentiation in vitro and ovariectomy induced bone loss in vivo. Bone 46(4):1089-1099, 2010 PubMed Abstract
  23. Igl, W.; Johansson, A.; Wilson, J.F.; Wild, S.H.; Polasek, O.; Hayward, C.; Vitart, V.; Hastie, N.; Rudan, P.; Gnewuch, C.; Schmitz, G.; Meitinger, T.; Pramstaller, P.P.; Hicks, A.A.; Oostra, B.A.; van Duijn, C.M.; Rudan, I.; Wright, A.; Campbell, H. and Gyllensten, U. Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels.
    PLoS Genet.     6(1):e1000798, 2010
    PubMed Abstract
  24. Jackson, C.A.; Hutchison, A.; Dennis, M.S.; Wardlaw, J.M.; Lindgren, A.; Norrving, B.; Anderson, C.S.; Hankey, G.J.; Jamrozik, K.; Appelros, P. and Sudlow, C.L. Differing risk factor profiles of ischemic stroke subtypes: evidence for a distinct lacunar arteriopathy? Stroke 41(4):624-629, 2010
    PubMed Abstract
  25. Johansson, A.; Marroni, F.; Hayward, C.; Franklin, C.S.; Kirichenko, A.V.; Jonasson, I.; Hicks, A.A.; Vitart, V.; Isaacs, A.; Axenovich, T.; Campbell, S.; Floyd, J.; Hastie, N.; Knott, S.; Lauc, G.; Pichler, I.; Rotim, K.; Wild, S.H.; Zorkoltseva, I.V.; Wilson, J.F.; Rudan, I.; Campbell, H.; Pattaro, C.; Pramstaller, P.; Oostra, B.A.; Wright, A.F.; van Duijn, C.M.; Aulchenko, Y.S. and Gyllensten, U. Linkage and Genome-wide Association Analysis of Obesity-related Phenotypes: Association of Weight With the MGAT1 Gene.
    Obesity.(Silver.Spring)     18(4):803-8, 2010 PubMed Abstract
  26. Kitchen, R.R.; Sabine, V.S.; Sims, A.H.; Macaskill, E.J.; Renshaw, L.; Thomas, J.S.; van Hemert, J.I.; Dixon, J.M. and Bartlett, J.M. Correcting for intra-experiment variation in Illumina BeadChip data is necessary to generate robust gene-expression profiles.
    BMC Genomics     11:134, 2010
    PubMed Abstract
  27. Kocanova, S.; Kerr, E.A.; Rafique, S.; Boyle, S.; Katz, E.; Caze-Subra, S.; Bickmore, W.A. and Bystricky, K. Activation of estrogen-responsive genes does not require their nuclear co-localization.
    PLoS Genet. 6(4):e1000922, 2010
    PubMed Abstract
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